Article
Melatonin receptors in diabetes: a potential new therapeutical target?
European journal of pharmacology - 5 Dec 2014
She Meihua, Laudon Moshe, Yin Weidong
Abstract excerpt
Melatonin is synthesized and secreted mainly by the pineal gland in a circadian fashion, and it thus mediates endogenous circadian rhythms and influences other physiological functions. Both the G-protein coupled receptors MT1 (encoded by MTNR1A) and MT2 (encoded by MTNR1B) in mammals mediate the actions of melatonin. Evidence from in vivo and in vitro studies proved a key role of melatonin in the regulation of...
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