Article
[Involvement of melatonin MT2 receptor mutants in type 2 diabetes development].
Medecine sciences : M/S - 1 Jan 2000
Karamitri Angeliki, Vincens Monique, Chen Min, Jockers Ralf
Abstract excerpt
Genetic and environmental factors participate in the development of type 2 diabetes (T2D). Genome-wide association studies have revealed new genetic variants associated with T2D, including the rs10830963 variant located in the intron of the MTNR1B gene. This gene encodes the melatonin MT2 receptor, a member of the family of G protein-coupled receptors involved in the regulation of circadian and seasonal rhythms....
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