Article
Association between the melatonin receptor 1B gene polymorphism on the risk of type 2 diabetes, impaired glucose regulation: a meta-analysis.
PloS one - 1 Jan 2012
Xia Qing, Chen Zi-Xian, Wang Yi-Chao, Ma Yu-Shui, Zhang Feng, Che Wu, Fu Da, Wang Xiao-Feng
Abstract excerpt
BACKGROUND: Melatonin receptor 1B (MTNR1B) belongs to the seven-transmembrane G protein-coupled receptor superfamily involved in insulin secretion, which has attracted considerable attention as a candidate gene for type 2 diabetes (T2D) since it was first identified as a loci associated with fasting plasma glucose level through genome wide association approach. The relationship between MTNR1B and T2D has been...
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