Article
A microarray platform and novel SNP calling algorithm to evaluate Plasmodium falciparum field samples of low DNA quantity.
BMC genomics - 26 Aug 2014
Jacob Christopher G, Tan John C, Miller Becky A, Tan Asako, Takala-Harrison Shannon, Ferdig Michael T, Plowe Christopher V
Abstract excerpt
BACKGROUND: Analysis of single nucleotide polymorphisms (SNPs) derived from whole-genome studies allows for rapid evaluation of genome-wide diversity, and genomic epidemiology studies of Plasmodium falciparum provide insights into parasite population structure, gene flow, drug resistance and vaccine development. In areas with adequate cold chain facilities, large volumes of leukocyte-depleted patient blood can be...
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