Article
A general SNP-based molecular barcode for Plasmodium falciparum identification and tracking.
Malaria journal - 29 Oct 2008
Daniels Rachel, Volkman Sarah K, Milner Danny A, Mahesh Nira, Neafsey Daniel E, Park Daniel J, Rosen David, Angelino Elaine, Sabeti Pardis C, Wirth Dyann F, Wiegand Roger C
Abstract excerpt
BACKGROUND: Single nucleotide polymorphism (SNP) genotyping provides the means to develop a practical, rapid, inexpensive assay that will uniquely identify any Plasmodium falciparum parasite using a small amount of DNA. Such an assay could be used to distinguish recrudescence from re-infection in drug trials, to monitor the frequency and distribution of specific parasites in a patient population undergoing drug...
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