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Article

An optimized microarray platform for assaying genomic variation in Plasmodium falciparum field populations.

Genome biology - 1 Jan 2011

Tan John C, Miller Becky A, Tan Asako, Patel Jigar J, Cheeseman Ian H, Anderson Tim J C, Manske Magnus, Maslen Gareth, Kwiatkowski Dominic P, Ferdig Michael T

Abstract excerpt

We present an optimized probe design for copy number variation (CNV) and SNP genotyping in the Plasmodium falciparum genome. We demonstrate that variable length and isothermal probes are superior to static length probes. We show that sample preparation and hybridization conditions mitigate the effects of host DNA contamination in field samples. The microarray and workflow presented can be used to identify CNVs...

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Share to Chromosomal and Genetic Variations
Share to DNA Copy Number Variations

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Evolution and Genetic Dynamics

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Share to Oligonucleotide Array Sequence Analysis

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Share to Polymorphism, Single Nucleotide

Source

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Identifiers

PMID: 21477297
DOI: 10.1186/gb-2011-12-4-r35
PMCID: PMC3218861

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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