Heterogeneity in the inter-tumor transcriptome of high risk prostate cancer.

doi:10.1186/s13059-014-0426-y

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Article

Heterogeneity in the inter-tumor transcriptome of high risk prostate cancer.

Genome biology - 26 Aug 2014

Wyatt Alexander W, Mo Fan, Wang Kendric, McConeghy Brian, Brahmbhatt Sonal, Jong Lina, Mitchell Devon M, Johnston Rebecca L, Haegert Anne, Li Estelle, Liew Janet, Yeung Jake, Shrestha Raunak, Lapuk Anna V, McPherson Andrew, Shukin Robert, Bell Robert H, Anderson Shawn, Bishop Jennifer, Hurtado-Coll Antonio, Xiao Hong, Chinnaiyan Arul M, Mehra Rohit, Lin Dong, Wang Yuzhuo, Fazli Ladan, Gleave Martin E, Volik Stanislav V, Collins Colin C

Abstract excerpt

BACKGROUND: Genomic analyses of hundreds of prostate tumors have defined a diverse landscape of mutations and genome rearrangements, but the transcriptomic effect of this complexity is less well understood, particularly at the individual tumor level. We selected a cohort of 25 high-risk prostate tumors, representing the lethal phenotype, and applied deep RNA-sequencing and matched whole genome sequencing,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25155515
DOI: 10.1186/s13059-014-0426-y
PMCID: PMC4169643

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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