Article
RNA-seq analysis of prostate cancer in the Chinese population identifies recurrent gene fusions, cancer-associated long noncoding RNAs and aberrant alternative splicings.
Cell research - 1 May 2012
Ren Shancheng, Peng Zhiyu, Mao Jian-Hua, Yu Yongwei, Yin Changjun, Gao Xin, Cui Zilian, Zhang Jibin, Yi Kang, Xu Weidong, Chen Chao, Wang Fubo, Guo Xinwu, Lu Ji, Yang Jun, Wei Min, Tian Zhijian, Guan Yinghui, Tang Liang, Xu Chuanliang, Wang Linhui, Gao Xu, Tian Wei, Wang Jian, Yang Huanming, Wang Jun, Sun Yinghao
Abstract excerpt
There are remarkable disparities among patients of different races with prostate cancer; however, the mechanism underlying this difference remains unclear. Here, we present a comprehensive landscape of the transcriptome profiles of 14 primary prostate cancers and their paired normal counterparts from the Chinese population using RNA-seq, revealing tremendous diversity across prostate cancer transcriptomes with...
Read the complete abstract on PubMedTopics
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