Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Kallikrein-related peptidase 7 (KLK7) is a proliferative factor that is aberrantly expressed in human colon cancer

6 Aug 2014

Abstract excerpt

Emerging evidence indicates that serine proteases of the tissue kallikrein-related peptidases family (KLK) are implicated in tumorigenesis. We recently reported the ectopic expression of KLK4 and KLK14 in colonic cancers and their signaling to control cell proliferation. Human tissue kallikrein-related peptidase 7 (KLK7) is often dysregulated in many cancers; however, its role in colon tumorigenesis has not yet...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Coagulation, Bradykinin, Polyphosphates, and Angioedema
Share to Peptidase Inhibition and Analysis
Share to Phytochemical compounds biological activities

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25153388
DOI: 10.1515/hsz-2014-0142

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Kallikrein-related peptidase 7 (KLK7) is a proliferative factor that is aberrantly expressed in human colon cancerPMID 25153388Read ↗

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells.Semantic proximity Read ↗

Aberrant expression of kallikrein‐related peptidase 7 is correlated with human melanoma aggressiveness by stimulating cell migration and invasionSemantic proximity Read ↗

Kallikrein-Related Peptidase 6 (KLK6) as a Contributor toward an Aggressive Cancer Cell Phenotype: A Potential Role in Colon Cancer Peritoneal Metastasis.Semantic proximity Read ↗

Kallikrein 6 is a mediator of K-RAS-dependent migration of colon carcinoma cellsSemantic proximity Read ↗

Kallikrein-related peptidases represent attractive therapeutic targets for ovarian cancerSemantic proximity Read ↗

A functional role for Smad7 in sustaining colon cancer cell growth and survivalSemantic proximity Read ↗

Three dysregulated miRNAs control kallikrein 10 expression and cell proliferation in ovarian cancerSemantic proximity Read ↗

Expression analysis of the human kallikrein 7 (KLK7) in breast tumors: a new potential biomarker for prognosis of breast carcinomaSemantic proximity Read ↗

Silencing of PTK7 in colon cancer cells: caspase-10-dependent apoptosis via mitochondrial pathway.Semantic proximity Read ↗

Kallikrein-related peptidase 7 overexpression in melanoma cells modulates cell adhesion leading to a malignant phenotype.Semantic proximity Read ↗

PTK7, a Catalytically Inactive Receptor Tyrosine Kinase, Increases Oncogenic Phenotypes in Xenograft Tumors of Esophageal Squamous Cell Carcinoma KYSE-30 Cells.Semantic proximity Read ↗

Overexpression of the human tissue kallikrein genes KLK4, 5, 6, and 7 increases the malignant phenotype of ovarian cancer cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.