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Article

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells.

FEBS open bio - 1 May 2026

Haffani Yosr Z, Dreyer Tobias, Naim Meriem, Dico Rea Lo, Ignatenko Natalia A, Magdolen Viktor, Darmoul Dalila

Abstract excerpt

Colorectal cancer (CRC) incidence and mortality continue to rise globally and new prognostic biomarkers are required for the development of targeted therapies. Several studies have suggested that tissue kallikrein-related peptidases (KLKs), including KLK7, contribute to tumorigenesis. We previously demonstrated KLK7's tumor-promoting role both in vitro and in vivo, but its role in CRC metastasis remains unclear....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41335524
DOI: 10.1002/2211-5463.70171
PMCID: PMC13145359

Genes

KLK7
MSN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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