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Article

Kallikrein-Related Peptidase 6 (KLK6) as a Contributor toward an Aggressive Cancer Cell Phenotype: A Potential Role in Colon Cancer Peritoneal Metastasis.

Biomolecules - 19 Jul 2022

Bouzid Hayet, Soualmia Feryel, Oikonomopoulou Katerina, Soosaipillai Antoninus, Walker Francine, Louati Khaoula, Lo Dico Rea, Pocard Marc, El Amri Chahrazade, Ignatenko Natalia A, Darmoul Dalila

Abstract excerpt

Kallikrein-related peptidases (KLKs) are implicated in many cancer-related processes. KLK6, one of the 15 KLK family members, is a promising biomarker for diagnosis of many cancers and has been associated with poor prognosis of colorectal cancer (CRC) patients. Herein, we evaluated the expression and cellular functions of KLK6 in colon cancer-derived cell lines and in clinical samples from CRC patients. We showed...

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Identifiers

PMID: 35883559
DOI: 10.3390/biom12071003
PMCID: PMC9312869

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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