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Article

Kallikrein-related peptidases represent attractive therapeutic targets for ovarian cancer

17 Aug 2018

Abstract excerpt

INTRODUCTION: Aberrant levels of kallikrein-related peptidases (KLK1-15) have been linked to cancer cell proliferation, invasion and metastasis. In ovarian cancer, the KLK proteolytic network has a crucial role in the tissue and tumor microenvironment. Publically available ovarian cancer genome and expression data from multiple patient cohorts show an upregulation of most KLKs. Areas covered: Here, we review the...

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Share to Coagulation, Bradykinin, Polyphosphates, and Angioedema
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 30114962
DOI: 10.1080/14728222.2018.1512587

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