Article
The genetics of murine Hox loci: TAMERE, STRING, and PANTHERE to engineer chromosome variants.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2014
Tschopp Patrick, Duboule Denis
Abstract excerpt
Following their duplications at the base of the vertebrate clade, Hox gene clusters underwent remarkable sub- and neo-functionalization events. Many of these evolutionary innovations can be associated with changes in the transcriptional regulation of their genes, where an intricate relationship between the structure of the gene cluster and the architecture of the surrounding genomic landscape is at play. Here, we...
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