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Article

Genetic variation in CYP3A43 is associated with response to antipsychotic medication.

Journal of neural transmission (Vienna, Austria : 1996) - 1 Jan 2015

Brandl Eva J, Chowdhury Nabilah I, Tiwari Arun K, Lett Tristram A P, Meltzer Herbert Y, Kennedy James L, Müller Daniel J

Abstract excerpt

Genetic variation in cytochrome enzymes is known to affect drug metabolism and influence treatment response. Recently, the rs472660 variant in CYP3A43 has been associated with olanzapine response and clearance. In this study, we investigated the impact of rs472660 and the putatively functional marker rs680055 on antipsychotic response. We genotyped the rs472660 and rs680055 single nucleotide polymorphisms (SNPs)...

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Source

Identifiers

PMID: 25150845
DOI: 10.1007/s00702-014-1298-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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