Article
No influence of CYP3A43 rs472660G> A on steady-state serum olanzapine concentrations in white psychiatric patients.
Pharmacogenetics and genomics - 1 May 2014
Söderberg Mao M, Molden Espen, Dahl Marja-Liisa
Abstract excerpt
The potential involvement of CYP3A43 in systemic olanzapine (OLA) metabolism has been suggested by one reported association between the intronic polymorphism CYP3A43 rs472660G>A and OLA clearance in 235 White and African-American patients. Trough plasma OLA concentrations in AA carriers were predicted on average 48% lower than in GG carriers. In the current study, we evaluated this finding by genotyping 374 White...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
