Article
The identification of novel genetic variants associated with antipsychotic treatment response outcomes in first-episode schizophrenia patients.
Pharmacogenetics and genomics - 1 May 2016
Drögemöller Britt I, Emsley Robin, Chiliza Bonginkosi, van der Merwe Lize, Wright Galen E B, Daya Michelle, Hoal Eileen, Malhotra Anil K, Lencz Todd, Robinson Delbert G, Zhang Jian-Ping, Asmal Laila, Niehaus Dana J H, Warnich Louise
Abstract excerpt
BACKGROUND: Although antipsychotics are integral to the treatment of schizophrenia, drug efficacy varies between patients. Although it has been shown that antipsychotic treatment response outcomes are heritable, our understanding of the genetic factors that are involved remains incomplete. Therefore, this study aims to use an unbiased scan of the genome to identify the genetic variants contributing toward...
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