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Article

Concordant B-cell precursor acute lymphoblastic leukemia in non-twinned siblings.

Blood cells, molecules & diseases - 1 Jan 2015

Pombo-de-Oliveira Maria S, Emerenciano Mariana, Winn Ana Paula Ferreira Freund, Costa Imaruí, Mansur Marcela B, Ford Anthony M

Abstract excerpt

Associating the risk of childhood acute lymphoblastic leukemia (ALL) with genetic predisposition is still a challenge. Here, we discuss two non-twinned sibs (girl and boy) diagnosed with B-cell precursor (BCP-ALL) and ETV6-RUNX1. BCP-ALL clinical onset occurred 10months apart from each diagnosis. One child is alive in complete continuous remission, whereas, the other relapsed and evolved to death with resistance...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25150625
DOI: 10.1016/j.bcmd.2014.07.011

Genes

ETV6
IKZF1
RUNX1
GSTM1
GSTT1
NQO1
PTPRJ

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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