Allogeneic HCT for adults with B-cell precursor acute lymphoblastic leukemia harboring IKZF1 gene mutations. A study by the Acute Leukemia Working Party of the EBMT.

doi:10.1038/s41409-020-01139-z

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Allogeneic HCT for adults with B-cell precursor acute lymphoblastic leukemia harboring IKZF1 gene mutations. A study by the Acute Leukemia Working Party of the EBMT.

Bone marrow transplantation - 1 May 2021

Giebel Sebastian, Labopin Myriam, Socié Gerard, Beauvais David, Klein Stefan, Wagner-Drouet Eva Maria, Blaise Didier, Nguyen-Quoc Stephanie, Bourhis Jean Henri, Thiebaut Anne, Labussière-Wallet Hélène, Charbonnier Amandine, Berceanu Ana, Diez-Martin José Luis, Fegueux Nathalie, Esteve Jordi, Nagler Arnon, Mohty Mohamad

Abstract excerpt

The presence of IKZF1 gene mutations is associated with poor prognosis of B-cell precursor acute lymphoblastic leukemia (BCP-ALL). The goal of this retrospective study was to evaluate outcome of allogeneic hematopoietic cell transplantation (allo-HCT) in this population. Ninety-five patients transplanted in first (n = 75) or second (n = 20) complete remission (CR) from either HLA-matched sibling (n = 32),...

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PMID: 33235351
DOI: 10.1038/s41409-020-01139-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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