Article
[Effects of histone H3 K4L and K36L mutations on the cell growth and the transcription of GAL1, SSA3 and PHO5 in Saccharomyces cerevisiae].
Yi chuan = Hereditas - 1 Aug 2014
Li Fen, Yang Jinghui, Wu Xiuli, Zhang Weilin, Wang Guanfeng, Yue Xiaojie
Abstract excerpt
Post-translational modifications of histones, such as acetylation and methylation, have a pivotal role in regulating gene expression and cell growth. To elucidate the different roles and importance of H3K4 and H3K36 modifications in expression of inducible genes such as Cal1, SSA3, PHO5 and the growth of yeast cell, we constructed three different yeast mutant strains carrying mutations of lysine 4, 36, or both to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.