Article
[Control levels of Sin3 histone deacetylase for spontaneous and UV-induced mutagenesis in yeasts Saccharomyces cerevisiae].
Genetika - 1 Jan 2014
Lebovka I Iu, Kozhina T N, Fedorova I V, Peshekhonov V T, Evstiukhina T A, Chernenkov A Iu, Korolev V G
Abstract excerpt
SIN3 gene product operates as a repressor for a huge amount of genes in Saccharomyces cerevisiae. Sin3 protein with a mass of about 175 kDa is a member of the RPD3 protein complex with an assessed mass of greater than 2 million Da. It was previously shownthat RPD3 gene mutations influence recombination and repair processes in S. cerevisiae yeasts. We studied the impacts of the sin3 mutation on UV-light...
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