Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A modified method for whole exome resequencing from minimal amounts of starting DNA.

PloS one - 1 Jan 2012

Kozarewa Iwanka, Rosa-Rosa Juan Manuel, Wardell Christopher P, Walker Brian A, Fenwick Kerry, Assiotis Ioannis, Mitsopoulos Costas, Zvelebil Marketa, Morgan Gareth J, Ashworth Alan, Lord Christopher J, J Christopher

Abstract excerpt

Next generation DNA sequencing (NGS) technologies have revolutionized the pace at which whole genome and exome sequences can be generated. However, despite these advances, many of the methods for targeted resequencing, such as the generation of high-depth exome sequences, are somewhat limited by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Line
Share to DNA
Share to Exome

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Library

Share to Genomics

Share to Laboratories

Share to Polymerase Chain Reaction

Share to Sequence Analysis, DNA

Source

Open in PubMed Open full text

Identifiers

PMID: 22403682
DOI: 10.1371/journal.pone.0032617
PMCID: PMC3293839

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22403682-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A modified method for whole exome resequencing from minimal amounts of starting DNA.PMID 22403682Read ↗

Assessment of whole genome amplification for sequence capture and massively parallel sequencing.Semantic proximity Read ↗

Use of FFPE-derived DNA in next generation sequencing: DNA extraction methodsSemantic proximity Read ↗

CUTseq is a versatile method for preparing multiplexed DNA sequencing libraries from low-input samplesSemantic proximity Read ↗

Performance comparison of four exome capture systems for deep sequencing.Semantic proximity Read ↗

Evaluation of Exome Sequencing to Estimate Tumor Burden in PlasmaSemantic proximity Read ↗

Use of FFPE-Derived DNA in Next Generation Sequencing: DNA extraction methodsSemantic proximity Read ↗

Reliable detection of somatic mutations in solid tissues by laser-capture microdissection and low-input DNA sequencing.Semantic proximity Read ↗

Applications of next-generation whole exome sequencing.Semantic proximity Read ↗

Whole exome sequencing (WES) on formalin-fixed, paraffin-embedded (FFPE) tumor tissue in gastrointestinal stromal tumors (GIST).Semantic proximity Read ↗

Does massively parallel DNA resequencing signify the end of histopathology as we know it?Semantic proximity Read ↗

Optimizing nucleic acid extraction and transcriptome evaluation from low-input, fixed clinical samplesSemantic proximity Read ↗

NGS method for parallel processing of high quality, damaged or fragmented input material using target enrichmentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.