Article
An analysis of genetic factors related to risk of inflammatory bowel disease and colon cancer.
Cancer epidemiology - 1 Oct 2014
Ryan Bríd M, Wolff Roger K, Valeri Nicola, Khan Mohammed, Robinson Dillon, Paone Alessio, Bowman Elise D, Lundgreen Abbie, Caan Bette, Potter John, Brown Derek, Croce Carlo, Slattery Martha L, Harris Curtis C
Abstract excerpt
BACKGROUND AND AIMS: Patients with inflammatory bowel disease (IBD) have a higher risk of developing colorectal cancer than the general population. Genome-wide association studies have identified and replicated several loci associated with risk of IBD; however, it is currently unknown whether these loci are also associated with colon cancer risk. METHODS: We selected 15 validated SNPs associated with risk of...
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