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Association of signal transducer and activator of transcription 4 genetic variants with extra-intestinal manifestations in inflammatory bowel disease.

Life sciences - 24 Apr 2010

Moon Chang Mo, Cheon Jae Hee, Kim Seung Won, Shin Dong-Jik, Kim Eun Soo, Shin Eun-Soon, Kang Yoon, Park Jae Jun, Hong Sung Pil, Nam Su Youn, Kim Tae Il, Kim Won Ho

Abstract excerpt

AIMS: The STAT4 gene encodes a transcription factor which plays an important role in the development of inflammation of many immune-mediated diseases. We investigated the relationship between STAT4 single nucleotide polymorphisms (SNPs) and susceptibility to ulcerative colitis (UC) and Crohn's disease (CD) and disease phenotypes in the Korean population. MAIN METHODS: We performed a case-control association study...

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Asian People
Case-Control Studies
Child
Colitis, Ulcerative
Crohn Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

STAT4 Transcription Factor

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Identifiers

PMID: 20176035
DOI: 10.1016/j.lfs.2010.02.016

Genes

STAT4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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Association of signal transducer and activator of transcription 4 genetic variants with extra-intestinal manifestations in inflammatory bowel disease.PMID 20176035Read ↗

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Abnormal genetic and epigenetic changes in signal transducer and activator of transcription 4 in the pathogenesis of inflammatory bowel diseases.Semantic proximity Read ↗

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Association between STAT3 gene polymorphisms and ulcerative colitis susceptibility: a case-control study in the Chinese Han population.Semantic proximity Read ↗

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The G2964A polymorphism of the STAT6 gene in inflammatory bowel disease.Semantic proximity Read ↗

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Association of the STAT4 gene with increased susceptibility for some immune-mediated diseases.Semantic proximity Read ↗

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