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Article

Gating characteristics control glutamate receptor distribution and trafficking in vivo.

Current biology : CB - 8 Sept 2014

Petzoldt Astrid G, Lee Yü-Hien, Khorramshahi Omid, Reynolds Eric, Plested Andrew J R, Herzel Hanspeter, Sigrist Stephan J

Abstract excerpt

Glutamate-releasing synapses dominate excitatory release in the brain. Mechanisms governing their assembly are of major importance for circuit development and long-term plasticity underlying learning and memory. AMPA/Kainate-type glutamate receptors (GluRs) are tetrameric ligand-gated ion channels that open their ion-conducting pores in response to binding of the neurotransmitter. Changes in subunit composition...

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Identifiers

PMID: 25131677
DOI: 10.1016/j.cub.2014.07.051

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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