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Article

Block of kainate receptor desensitization uncovers a key trafficking checkpoint.

Neuron - 21 Dec 2006

Priel Avi, Selak Sanja, Lerma Juan, Stern-Bach Yael

Abstract excerpt

A prominent feature of ionotropic glutamate receptors from the AMPA and kainate subtypes is their profound desensitization in response to glutamate-a process thought to protect the neuron from overexcitation. In AMPA receptors, it is well established that desensitization results from rearrangements of the interface formed between agonist-binding domains of adjacent subunits; however, it is unclear how this...

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Identifiers

PMID: 17178406
DOI: 10.1016/j.neuron.2006.12.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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