Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Activated macrophages create lineage-specific microenvironments for pancreatic acinar- and β-cell regeneration in mice.

Gastroenterology - 1 Nov 2014

Criscimanna Angela, Coudriet Gina M, Gittes George K, Piganelli Jon D, Esni Farzad

Abstract excerpt

BACKGROUND & AIMS: Although the cells that contribute to pancreatic regeneration have been widely studied, little is known about the mediators of this process. During tissue regeneration, infiltrating macrophages debride the site of injury and coordinate the repair response. We investigated the role of macrophages in pancreatic regeneration in mice. METHODS: We used a saporin-conjugated antibody against CD11b to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acinar Cells
Share to CD11b Antigen

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cellular Microenvironment

Share to Diphtheria Toxin

Share to Immunoconjugates

Share to Insulin-Secreting Cells

Share to Macrophage Activation

Share to Regeneration

Source

Identifiers

PMID: 25128759
DOI: 10.1053/j.gastro.2014.08.008

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Activated macrophages create lineage-specific microenvironments for pancreatic acinar- and β-cell regeneration in mice.PMID 25128759Read ↗

Macrophage phenotypic switch orchestrates the inflammation and repair/regeneration following acute pancreatitis injury.Semantic proximity Read ↗

Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferationSemantic proximity Read ↗

Macrophages in the pancreas: Villains by circumstances, not necessarily by actions.Semantic proximity Read ↗

Interleukin 17-producing γδT cells promote hepatic regeneration in mice.Semantic proximity Read ↗

Altered macrophage phenotype transition impairs skeletal muscle regeneration.Semantic proximity Read ↗

Cathepsin B-Mediated Activation of Trypsinogen in Endocytosing Macrophages Increases Severity of Pancreatitis in Mice.Semantic proximity Read ↗

Minireview: Emerging Concepts in Islet Macrophage Biology in Type 2 DiabetesSemantic proximity Read ↗

Macrophage Contact Dependent and Independent TLR4 Mechanisms Induce β-Cell Dysfunction and Apoptosis in a Mouse Model of Type 2 DiabetesSemantic proximity Read ↗

Inhibition of Notch activity suppresses hyperglycemia-augmented polarization of macrophages to the M1 phenotype and alleviates acute pancreatitis.Semantic proximity Read ↗

Dendritic cells promote pancreatic viability in mice with acute pancreatitis.Semantic proximity Read ↗

Concise Review: New Insights Into the Role of Macrophages in β-Cell ProliferationSemantic proximity Read ↗

In situ kinetics of acinar, duct, and inflammatory cells in duct ligation-induced pancreatitis in rats.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.