Article
Altered macrophage phenotype transition impairs skeletal muscle regeneration.
The American journal of pathology - 1 Apr 2014
Wang Hanzhou, Melton David W, Porter Laurel, Sarwar Zaheer U, McManus Linda M, Shireman Paula K
Abstract excerpt
Monocyte/macrophage polarization in skeletal muscle regeneration is ill defined. We used CD11b-diphtheria toxin receptor transgenic mice to transiently deplete monocytes/macrophages at multiple stages before and after muscle injury induced by cardiotoxin. Fat accumulation within regenerated muscl...
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