Article
[Mutant alleles associated to chloroquine and sulfadoxine-pyrimethanime resistance in Plasmodium falciparum of the Ecuador-Peru and Ecuador-Colombia borders].
Revista peruana de medicina experimental y salud publica - 1 Apr 2014
Arróspide Nancy, Hijar-Guerra Gisely, de Mora Doménica, Diaz-Cortéz César Eduardo, Veloz-Perez Raúl, Gutierrez Sonia, Cabezas-Sánchez César
Abstract excerpt
The frequency of mutations in pfCRT and DHFR/DHPS genes of Plasmodium falciparum associated with resistance to chloroquine and sulfadoxine-pyrimethamine was evaluated in 83 strains from the districts of Esmeralda and Machala, located on the borders of Ecuador-Peru and Ecuador-Colombia in 2002. Polymerase chain reaction (PCR), conventional and its variants, was used. Mutations in the pfCRT gene were found in more...
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