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Article

Origin and dissemination across the Colombian Andes mountain range of sulfadoxine-pyrimethamine resistance in Plasmodium falciparum.

Antimicrobial agents and chemotherapy - 1 Aug 2010

Corredor Vladimir, Murillo Claribel, Echeverry Diego F, Benavides Julie, Pearce Richard J, Roper Cally, Guerra Angela P, Osorio Lyda

Abstract excerpt

The therapeutic efficacy of sulfadoxine-pyrimethamine (SP) in treating uncomplicated Plasmodium falciparum malaria is unevenly distributed in Colombia. The Andes mountain range separates regions in the west where malaria is endemic from those in the east and constitutes a barrier against gene flow and the dispersal of parasite populations. The distribution of dhfr and dhps genotypes of 146 P. falciparum samples...

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Identifiers

PMID: 20498318
DOI: 10.1128/AAC.00036-10
PMCID: PMC2916335

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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