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Article

pfcrt Polymorphism and the spread of chloroquine resistance in Plasmodium falciparum populations across the Amazon Basin.

The Journal of infectious diseases - 15 Jul 2004

Vieira Pedro Paulo, Ferreira Marcelo Urbano, Alecrim Maria das Gracas, Alecrim Wilson D, da Silva Luiz Hidelbrando P, Sihuincha Moises M, Joy Deirdre A, Mu Jianbing, Su Xin-Zhuan, Zalis Mariano G

Abstract excerpt

The widespread occurrence of drug-resistant malaria parasites in South America presents a formidable obstacle to disease control in this region. To characterize parasite populations and the chloroquine-resistance profile of Plasmodium falciparum in the Amazon Basin, we analyzed a DNA segment of the pfcrt gene, spanning codons 72-76, and genotyped 15 microsatellite (MS) markers in 98 isolates from 6 areas of...

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PMID: 15216481
DOI: 10.1086/422006

Genes

MNT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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