Article
[Genotyping of the Plasmodium falciparum msp1 (block 2) and dhfr (codon 108) genes in field samples collected in four endemic Colombian localities].
Biomedica : revista del Instituto Nacional de Salud - 1 Mar 2006
Guerra Angela Patricia, Knudson Angélica, Nicholls Rubén Santiago, Galindo John Alexander, Ravid Zaava, Rahirant Sonia, Duarte Nidia, Chaparro-Olaya Jacqueline, Wasserman Moisés
Abstract excerpt
INTRODUCTION: Plasmodium falciparum is a highly polymorphic parasite, which allows it to evade the host's immune response, spread drug resistance and favours transmission. OBJECTIVES: To analyse the genetic diversity of P. falciparum populations in samples from four endemic localities in Colombia. MATERIALS AND METHODS: 123 blood samples were collected on filter paper from patients with non-complicated P....
Topics
- Animals
- Antimalarials
- Colombia
- Disease Transmission, Infectious
- Genetic Variation
- Genotype
- Humans
- Malaria, Falciparum
- Merozoite Surface Protein 1
- Plasmodium falciparum