Article
Revising antimalarial drug policy in Central America: experience in Panama.
Transactions of the Royal Society of Tropical Medicine and Hygiene - 1 Jul 2008
Calzada Jose E, Samudio Franklyn, Bayard Vicente, Obaldia Nicanor, de Mosca Itza B, Pascale Juan M
Abstract excerpt
Panama is the first country in the Central American region that has officially discarded chloroquine as a first-line drug to treat Plasmodium falciparum cases. Here we describe the clinical and molecular findings from autochthonous P. falciparum fatal cases, and the epidemiological situation that led to a change in the national antimalarial drug policy. Our results illustrate the potential pathogenicity of the...
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