Article
Studies on antimalarial drug susceptibility in Colombia, in relation to Pfmdr1 and Pfcrt.
Parasitology - 1 Apr 2008
Restrepo-Pineda E, Arango E, Maestre A, Do Rosário V E, Cravo P
Abstract excerpt
In Colombia, Plasmodium resistance to antimalarials such as chloroquine and antifolates is a serious problem. As a result, the national Colombian health authorities are monitoring the efficacy of alternative drugs and schemes. The study of genetic polymorphisms related with drug resistance is required in the region. In vitro responses to chloroquine, quinine, mefloquine, amodiaquine, desethylamodiaquine,...
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