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Article

ALS motor phenotype heterogeneity, focality, and spread: deconstructing motor neuron degeneration.

Neurology - 8 Sept 2009

Ravits John M, La Spada Albert R

Abstract excerpt

Heterogeneity of motor phenotypes is a clinically well-recognized fundamental aspect of amyotrophic lateral sclerosis (ALS) and is determined by variability of 3 independent primary attributes: body region of onset; relative mix of upper motor neuron (UMN) and lower motor neuron (LMN) deficits; a...

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Identifiers

PMID: 19738176
DOI: 10.1212/WNL.0b013e3181b6bbbd
PMCID: PMC2739608

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19738176-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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