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Article

Microfluidic genotyping by rapid serial PCR and high-speed melting analysis.

Clinical chemistry - 1 Oct 2014

Sundberg Scott O, Wittwer Carl T, Howell Renée M, Huuskonen Jarkko, Pryor Robert J, Farrar Jared S, Stiles Heather M, Palais Robert A, Knight Ivor T

Abstract excerpt

BACKGROUND: Clinical molecular testing typically batches samples to minimize costs or uses multiplex lab-on-a-chip disposables to analyze a few targets. In genetics, multiple variants need to be analyzed, and different work flows that rapidly analyze multiple loci in a few targets are attractive. METHODS: We used a microfluidic platform tailored to rapid serial PCR and high-speed melting (HSM) to genotype 4...

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Source

Identifiers

PMID: 25117377
DOI: 10.1373/clinchem.2014.223768

Genes

MTHFR

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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