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Article

Mpdz expression in the caudolateral substantia nigra pars reticulata is crucially involved in alcohol withdrawal.

Genes, brain, and behavior - 1 Nov 2014

Kruse L C, Walter N A R, Buck K J

Abstract excerpt

Association studies implicate the multiple PDZ domain protein (MUPP1/MPDZ) gene in risk for alcoholism in humans and alcohol withdrawal in mice. Although manipulation of the Mpdz gene by homologous recombination and bacterial artificial chromosome transgenesis has suggested that its expression affects alcohol withdrawal risk, the potential confounding effects of linked genes and developmental compensation...

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Source

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Identifiers

PMID: 25109596
DOI: 10.1111/gbb.12171
PMCID: PMC4241148

Genes

MPDZ

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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