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Article

Hot spot mutations in Finnish non-small cell lung cancers.

Lung cancer (Amsterdam, Netherlands) - 1 Sept 2016

Mäki-Nevala Satu, Sarhadi Virinder Kaur, Rönty Mikko, Kettunen Eeva, Husgafvel-Pursiainen Kirsti, Wolff Henrik, Knuuttila Aija, Knuutila Sakari

Abstract excerpt

OBJECTIVES: Non-small cell lung cancer (NSCLC) is a common cancer with a poor prognosis. The aim of this study was to screen Finnish NSCLC tumor samples for common cancer-related mutations by targeted next generation sequencing and to determine their concurrences and associations with clinical features. MATERIALS AND METHODS: Sequencing libraries were prepared from DNA isolated from formalin-fixed,...

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Source

Identifiers

PMID: 27565922
DOI: 10.1016/j.lungcan.2016.06.024

Genes

KRAS
EGFR
ERBB2
STK11
BRAF
CTNNB1
ERBB4
MET
NOTCH1
NRAS
PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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