Article
Sequencing of mutational hotspots in cancer-related genes in small cell neuroendocrine cervical cancer.
Gynecologic oncology - 1 Jun 2016
Frumovitz Michael, Burzawa Jennifer K, Byers Lauren A, Lyons Yasmin A, Ramalingam Preetha, Coleman Robert L, Brown Jubilee
Abstract excerpt
OBJECTIVES: Small cell cervical cancer is a rare malignancy with limited treatment options for recurrent disease. We sought to determine if tumor specimens of small cell cervical cancer harbor common somatic mutations and if any of these are actionable. METHODS: Using a registry of patients with neuroendocrine cervical cancer, we identified 44 patients with pure or mixed small cell cervical cancer who had...
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