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Article

[Screening for mutations in the hotspot mutation regions of PIK3CA gene in nasopharyngeal carcinoma].

Ai zheng = Aizheng = Chinese journal of cancer - 1 Jan 2007

Liu Peng, Li Da-Jiang, Qin Hai-De, Zhang Ru-Hua, Chen Li-Zhen, Zeng Yi-Xin

Abstract excerpt

BACKGROUND & OBJECTIVE: Recent studies showed high frequency of phosphatidylinositol 3-kinase catalytic alpha polypeptide (PIK3CA) mutations in various human cancers; notably, these mutations frequently locate in the hotspot mutation regions of PIK3CA exon 9 and exon 20 with functional significance in tumorigenesis, invasion, and anti-apoptosis. This study was to screen for mutations in the hotspot mutation...

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Share to Carcinoma, Squamous Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 22

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Source

Identifiers

PMID: 17222361

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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