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Article

Prognostic Landscape of TP53 Mutations in Hematologic Malignancies.

Cancer research and treatment - 1 Apr 2026

Jang Seo Yoon, Jang Joowon, Lee Jee-Soo, Seong Moon-Woo, Park Songyi, Byun Ja Min, Koh Youngil, Hong Junshik, Kim Inho, Yoon Sung-Soo, Shin Dong-Yeop

Abstract excerpt

PURPOSE: While TP53 mutations are well known to be associated with adverse prognosis in hematological diseases, their functional impact remains incompletely understood. This study examines the spectrum of TP53 mutations across various hematologic malignancies and evaluates their functional impact. MATERIALS AND METHODS: Using targeted sequencing panels, we analyzed TP53 mutations in the bone marrow aspiration...

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Source

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Identifiers

PMID: 40441759
DOI: 10.4143/crt.2025.297
PMCID: PMC13093014

Genes

TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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