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Novel inhibitors of human immunodeficiency virus type 2 infectivity

8 Aug 2014

Abstract excerpt

Human immunodeficiency virus type 2 (HIV-2) infects about two million people worldwide. HIV-2 has fewer treatment options than HIV-1, yet may evolve drug resistance more quickly. We have analysed several novel drugs for anti-HIV-2 activity. It was observed that 5-azacytidine, clofarabine, gemcitabine and resveratrol have potent anti-HIV-2 activity. The EC50 values for 5-azacytidine, clofarabine and resveratrol...

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PMID: 25103850
DOI: 10.1099/vir.0.069864-0

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