Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Current HIV therapeutics: mechanistic and chemical determinants of toxicity.

Current opinion in drug discovery & development - 1 Jan 2009

Chiao Stephanie K, Romero Donna L, Johnson Dale E

Abstract excerpt

This review discusses current recommendations for initial therapy in HIV-infected individuals and the toxicity of certain components of these therapeutic regimens. In developed regions, therapy is headed in a direction of individualized treatment where AIDS can be converted into a treatable, chronic disease that is characterized by viral loads below assay detection levels. In developing nations, where...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-HIV Agents
Share to Antiretroviral Therapy, Highly Active
Share to HIV-1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HIV Infections

Share to HIV Protease Inhibitors

Share to Mitochondria

Share to Reverse Transcriptase Inhibitors

Share to Structure-Activity Relationship

Source

Identifiers

PMID: 19152213

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Current HIV therapeutics: mechanistic and chemical determinants of toxicity.PMID 19152213Read ↗

Nucleoside reverse transcriptase inhibitor toxicity and mitochondrial DNASemantic proximity Read ↗

HIV Treatment and Associated Mitochondrial PathologySemantic proximity Read ↗

Mitochondrial dysfunctions in HIV infection and antiviral drug treatmentSemantic proximity Read ↗

Mitochondrial toxicity in HIV-infected patients both off and on antiretroviral treatment: a continuum or distinct underlying mechanisms?Semantic proximity Read ↗

Long term adverse effects related to nucleoside reverse transcriptase inhibitors: Clinical impact of mitochondrial toxicitySemantic proximity Read ↗

Mitochondrial Toxicogenomics for Antiretroviral Management: HIV Post-exposure Prophylaxis in Uninfected PatientsSemantic proximity Read ↗

Mitochondrial Toxicity in HAART: An Overview of In Vitro EvidenceSemantic proximity Read ↗

A brief overview of mechanisms of mitochondrial toxicity from NRTIs.Semantic proximity Read ↗

Mitochondrial dysfunction and antiretroviral nucleoside analog toxicities: what is the evidence?Semantic proximity Read ↗

Mitochondrial toxicity and HIV therapySemantic proximity Read ↗

Mechanisms of HIV and Nucleoside Reverse Transcriptase Inhibitor Injury to MitochondriaSemantic proximity Read ↗

Mitochondrial interference by anti-HIV drugs: mechanisms beyond Pol-γ inhibitionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.