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Article

Inhibition of human immunodeficiency virus by a new class of pyridine oxide derivatives.

Antimicrobial agents and chemotherapy - 1 Sept 2003

Stevens Miguel, Pannecouque Christophe, De Clercq Erik, Balzarini Jan

Abstract excerpt

A new class of pyridine oxide derivatives as inhibitors of human immunodeficiency virus type 1 (HIV-1) and/or HIV-2 replication in cell culture has been identified. The compounds, which specifically inhibit HIV-1, behave as typical nonnucleoside reverse transcriptase inhibitors (NNRTIs). The most active congener of this group, JPL-133 (UC-B3096), has a 50% effective concentration of 0.05 microg/ml for...

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Identifiers

PMID: 12937000
DOI: 10.1128/AAC.47.9.2951-2957.2003
PMCID: PMC182595

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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