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Article

X-ray structures of AMPA receptor-cone snail toxin complexes illuminate activation mechanism.

Science (New York, N.Y.) - 29 Aug 2014

Chen Lei, Dürr Katharina L, Gouaux Eric

Abstract excerpt

AMPA-sensitive glutamate receptors are crucial to the structural and dynamic properties of the brain, to the development and function of the central nervous system, and to the treatment of neurological conditions from depression to cognitive impairment. However, the molecular principles underlyin...

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Share to Crystallography, X-Ray
Share to Ion Channel Gating
Share to Ligands

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Protein Structure, Secondary

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Share to Receptors, AMPA

Source

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Identifiers

PMID: 25103405
DOI: 10.1126/science.1258409
PMCID: PMC4263349

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25103405-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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