Article
Effects of OPRM1 A118G polymorphism on epidural analgesia with fentanyl during labor: a meta-analysis.
Genetic testing and molecular biomarkers - 1 Oct 2013
Song Zheming, Du Boxiang, Wang Kai, Shi Xueyin
Abstract excerpt
BACKGROUND: Emerging evidence has shown that the most common polymorphism (A118G; rs1799971 A>G) in the μ-opioid receptor (OPRM1) gene may influence the response to labor analgesia, but individually published studies showed inconclusive results. OBJECTIVE: This meta-analysis aimed to derive a more precise estimation of the effects of the OPRM1 A118G polymorphism on epidural analgesia with fentanyl during labor....
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