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Article

Haplotype-based analysis of genes associated with risk of adverse skin reactions after radiotherapy in breast cancer patients.

International journal of radiation oncology, biology, physics - 1 Nov 2007

Suga Tomo, Ishikawa Atsuko, Kohda Masakazu, Otsuka Yoshimi, Yamada Shigeru, Yamamoto Naohito, Shibamoto Yuta, Ogawa Yoshihiro, Nomura Kuninori, Sho Keizen, Omura Motoko, Sekiguchi Kenji, Kikuchi Yuzo, Michikawa Yuichi, Noda Shuhei, Sagara Masashi, Ohashi Jun, Yoshinaga Shinji, Mizoe Junetsu, Tsujii Hirohiko, Iwakawa Mayumi, Imai Takashi

Abstract excerpt

PURPOSE: To identify haplotypes of single nucleotide polymorphism markers associated with the risk of early adverse skin reactions (EASRs) after radiotherapy in breast cancer patients. METHODS AND MATERIALS: DNA was sampled from 399 Japanese breast cancer patients who qualified for breast-conserving radiotherapy. Using the National Cancer Institute-Common Toxicity Criteria scoring system, version 2, the patients...

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Breast Neoplasms
Chi-Square Distribution
Genetic Markers
Haplotypes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Radiation Injuries

Radiation Tolerance

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Identifiers

PMID: 17889263
DOI: 10.1016/j.ijrobp.2007.06.021

Genes

LIG3
PTTG1

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