Article
DNA Methyltransferase Gene Polymorphisms for Prediction of Radiation-Induced Skin Fibrosis after Treatment of Breast Cancer: A Multifactorial Genetic Approach.
Cancer research and treatment - 1 Apr 2017
Terrazzino Salvatore, Deantonio Letizia, Cargnin Sarah, Donis Laura, Pisani Carla, Masini Laura, Gambaro Giuseppina, Canonico Pier Luigi, Genazzani Armando A, Krengli Marco
Abstract excerpt
PURPOSE: This study was conducted to investigate the role of four polymorphic variants of DNA methyltransferase genes as risk factors for radiation-induced fibrosis in breast cancer patients. We also assessed their ability to improve prediction accuracy when combined with mitochondrial haplogroup H, which we previously found to be independently associated with a lower hazard of radiation-induced fibrosis....
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