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Article

Genetic predictors of long-term toxicities after radiation therapy for breast cancer.

International journal of cancer - 15 Mar 2008

Kuptsova Nataliya, Chang-Claude Jenny, Kropp Silke, Helmbold Irmgard, Schmezer Peter, von Fournier Dietrich, Haase Wulf, Sautter-Bihl Marie Luise, Wenz Frederik, Onel Kenan, Ambrosone Christine B

Abstract excerpt

Telangiectasia and subcutaneous fibrosis are the most common late dermatologic side effects observed in response to radiation treatment. Radiotherapy acts on cancer cells largely due to the generation of reactive oxygen species (ROS). ROS also induce normal tissue toxicities. Therefore, we investigated if genetic variation in oxidative stress-related enzymes confers increased susceptibility to late skin...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18027873
DOI: 10.1002/ijc.23138

Genes

GSTA1
CAT
GSTM1
GSTP1
GSTT1
MPO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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