Trans-ethnic study confirmed independent associations of HLA-A*02:06 and HLA-B*44:03 with cold medicine-related Stevens-Johnson syndrome with severe ocular surface complications.

doi:10.1038/srep05981

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Trans-ethnic study confirmed independent associations of HLA-A02:06 and HLA-B44:03 with cold medicine-related Stevens-Johnson syndrome with severe ocular surface complications.

Scientific reports - 7 Aug 2014

Ueta Mayumi, Kannabiran Chitra, Wakamatsu Tais Hitomi, Kim Mee Kum, Yoon Kyung-Chul, Seo Kyoung Yul, Joo Choun-Ki, Sangwan Virender, Rathi Varsha, Basu Sayan, Shamaila Almas, Lee Hyo Seok, Yoon Sangchul, Sotozono Chie, Gomes José Álvaro Pereira, Tokunaga Katsushi, Kinoshita Shigeru

Abstract excerpt

Stevens-Johnson syndrome (SJS) and its severe variant, toxic epidermal necrolysis (TEN), are acute inflammatory vesiculobullous reactions of the skin and mucous membranes. Cold medicines including non-steroidal anti-inflammatory drugs and multi-ingredient cold medications are reported to be important inciting drugs. Recently, we reported that cold medicine related SJS/TEN (CM-SJS/TEN) with severe mucosal...

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PMID: 25099678
DOI: 10.1038/srep05981
PMCID: PMC4124463

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Trans-ethnic study confirmed independent associations of HLA-A*02:06 and HLA-B*44:03 with cold medicine-related Stevens-Johnson syndrome with severe ocular surface complications.PMID 25099678Read ↗

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