Article
Effect of Infectious Diseases on the Pathogenesis of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis.
Biological & pharmaceutical bulletin - 1 Jan 2017
Okamoto-Uchida Yoshimi, Nakamura Ryosuke, Sai Kimie, Imatoh Takuya, Matsunaga Kayoko, Aihara Michiko, Saito Yoshiro
Abstract excerpt
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe cutaneous adverse drug reactions. Recent studies have revealed that the prevalence of SJS/TEN is associated with genetic backgrounds, such as polymorphisms in human leukocyte antigens (HLAs). However, non-genetic factors contributing to the etiology of SJS/TEN are largely unknown. This study aimed to assess the involvement of...
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